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Blood samples were collected by venipuncture in Vacutainer CPT Mononuclear Cell Preparation Tubes (BD, Franklin Lakes, NJ) with sodium heparin, immediately placed in ice water, and then centrifuged at 2,000 g at 4C for 10 min
BPC-157 completely reversed the deleterious effects of systemic methylprednisolone on ligament healing, suggesting protective mechanisms that maintain healing capacity despite anti-inflammatory suppression
GSH, a potent reducing agent, donates electrons to disulfide bonds in the nanogels, initiating a thiol-disulfide exchange reaction
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Most significant studies were conducted in the 1980s and 1990s